How Adaptogens Support Stress and Focus

Adaptogens are plant-based substances that help your body manage stress and maintain balance without the highs and lows of stimulants like caffeine. They work by regulating stress hormones, improving energy production, and supporting mental clarity. Popular choices include ashwagandha, Rhodiola rosea, and ginseng, which have been used for centuries in health practices like Ayurveda and Chinese medicine.
Here’s what you need to know:
- Stress Reduction: Adaptogens regulate cortisol, your body’s primary stress hormone, helping you feel calmer during tough times.
- Focus and Energy: They improve focus and endurance by supporting energy production at a cellular level.
- Daily Use: Available in teas, supplements, and even non-alcoholic drinks, they’re easy to incorporate into your routine.
- Evidence: Studies suggest adaptogens can reduce stress, improve attention, and aid physical recovery, but more research is needed to confirm long-term effects.
Products like IMPOSSIBREW®’s non-alcoholic beers combine adaptogens with everyday convenience, making stress management more accessible. Always consult your GP before use, especially if you’re pregnant, breastfeeding, or on medication.
Adaptogens Explained : The Science Behind Ashwagandha, Rhodiola, and Ginseng
How Adaptogens Work to Reduce Stress and Focus
Adaptogens interact with your body's systems to help maintain balance when you're under stress. Let’s dive into the science behind how they work.
The Science Behind Adaptogens
The magic of adaptogens lies in how they interact with your hypothalamic-pituitary-adrenal (HPA) axis, the system that governs your body’s response to stress. When you're stressed, the HPA axis triggers the release of cortisol and other stress hormones. Adaptogens help regulate this process by balancing hormone release during stressful periods [2][3][7].
On a cellular level, adaptogens influence key stress mediators, such as molecular chaperones like HSP70, stress-activated protein kinases like JNK1, and transcription factors such as FOXO [2][3][4]. This helps stabilise cortisol levels and reduces oxidative stress throughout the body, which is crucial for improving your resilience to stress.
Adaptogens also enhance how efficiently your adrenal glands work. Instead of merely suppressing stress responses, they help your adrenal glands produce hormones more effectively, preventing cortisol spikes and supporting faster recovery [3][4].
Another benefit lies in their impact on energy production. For example, Rhodiola rosea enhances mitochondrial ATP production, which translates to better physical endurance and sharper mental performance [4].
Interestingly, adaptogens don't increase stress markers like cortisol or nitric oxide during acute stress. Instead, they help keep these levels steady - or even lower them - after physical or mental challenges, aiding recovery and improving resilience over time [3].
Top Adaptogens for Stress and Focus
Each adaptogen offers its own set of benefits, so you can choose the one that best suits your needs. Here are some of the most well-researched options:
- Rhodiola rosea: This adaptogen helps regulate the HPA axis and boosts serotonin levels, improving focus and endurance. Studies show it can prevent spikes in stress hormones and enhance stamina in both humans and animals [2][4].
- Ashwagandha (Withania somnifera): Known for reducing stress and anxiety, this Ayurvedic herb also improves sleep quality. Research shows it supports adrenal function and significantly lowers stress levels, as seen in products like IMPOSSIBREW®'s Social Blend™ [5].
- Panax ginseng: This adaptogen supports cognitive performance by inhibiting enzymes that break down stress hormones. It helps maintain hormone balance while boosting mental clarity and physical energy [3].
- Schisandra chinensis: This berry enhances both physical and mental resilience by regulating stress mediators. It’s a go-to for improving endurance and mental stamina [3].
| Adaptogen | Benefit | Key Mechanism | Effects |
|---|---|---|---|
| Rhodiola rosea | Mental fatigue, focus | Modulates HPA axis, increases serotonin | Reduces fatigue, boosts cognition |
| Ashwagandha | Anxiety, cortisol control | Lowers cortisol, supports adrenal glands | Promotes calm, reduces stress |
| Panax ginseng | Cognitive performance | Inhibits stress hormone breakdown | Improves clarity, boosts energy |
| Schisandra chinensis | Endurance, resilience | Regulates stress mediators | Enhances stamina, mental focus |
It’s also helpful to distinguish between primary and secondary adaptogens. Primary adaptogens, like the ones listed above, directly influence the HPA axis. Secondary adaptogens, on the other hand, support systems like the immune or endocrine system indirectly, without targeting stress hormone pathways [3]. This explains why combining different adaptogens can provide more comprehensive support.
Studies consistently highlight the ability of adaptogens to enhance mental performance and attention during stressful or tiring periods [2]. Animal research even suggests that combinations of adaptogens can extend lifespan and improve stress tolerance, showing their potential to offer benefits that go beyond immediate stress relief [2]. Together, these adaptogens present a range of scientifically-supported ways to help you focus and stay calm under pressure.
Research Evidence on Adaptogen Benefits
Scientific studies provide a clearer picture of how adaptogens work to manage stress and improve cognitive performance. These findings back up the earlier discussions on their stress-relieving and brain-boosting effects.
Stress Reduction and Cortisol Control
Research confirms that adaptogens can effectively lower stress levels. For instance, a randomised eight-week trial involving nearly 100 adults with chronic stress showed that ashwagandha supplementation significantly reduced stress scores compared to a placebo [5]. Participants reported being better equipped to handle daily pressures.
Adaptogens play a key role in balancing cortisol - the hormone released during stress. They help maintain cortisol at optimal levels, allowing the body to respond to stress without overreacting [3][4]. This balance prevents harmful cortisol spikes, reduces mental fatigue, and supports quicker recovery, which together enhance resilience to stress [3][4].
The European Medicines Agency has even acknowledged Rhodiola rosea as a stress-relieving adaptogen, a sign of its growing acceptance in clinical settings [4]. Beyond managing stress, emerging research suggests adaptogens also contribute to better brain function.
Cognitive Benefits of Adaptogens
Studies in both humans and animals have shown that adaptogens like Rhodiola rosea, Panax ginseng, and Schisandra chinensis can improve focus, mental stamina, and resistance to fatigue [2][4].
Among these, Rhodiola rosea stands out for its cognitive benefits. Research indicates it can extend attention span and reduce mental fatigue, especially in high-stress situations [2][4]. This is partly due to its ability to enhance mitochondrial ATP production, which improves cellular energy and boosts recovery [4]. In practical terms, this means fewer episodes of brain fog and better mental clarity.
Animal studies further highlight Rhodiola rosea's potential to improve endurance and speed up recovery [4]. Athletes using it have reported better stamina and faster post-exercise recovery, thanks to its impact on ATP synthesis and stress hormone regulation [4]. These findings suggest that adaptogens offer benefits not just for mental tasks but also for physical performance.
Additionally, adaptogens influence stress-related mediators like nitric oxide and heat shock proteins, which contribute to sharper focus and improved endurance [2][3][4]. This multi-faceted effect explains why users often feel both calmer and more alert when they take adaptogens regularly.
That said, experts urge caution. While adaptogens appear promising, the research is still evolving, and more robust clinical trials are needed to establish clear usage guidelines [6][7]. Large-scale studies and meta-analyses remain scarce, though reviews of current data suggest adaptogens may help manage stress and fatigue across various populations [6][8].
Several gaps in research still need addressing. For example, scientists are working to standardise adaptogen extracts and determine the best dosages for different groups [6]. There's also limited information on how adaptogens interact with medications or affect specific populations, such as older adults or individuals with chronic illnesses [6][8].
Even with these limitations, existing studies lay a strong groundwork for understanding how adaptogens can support stress relief and cognitive health in everyday life.
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How to Add Adaptogens to Your Daily Routine
Incorporating adaptogens into your day doesn’t have to mean upending your lifestyle. With the right approach and carefully chosen products, you can easily weave these stress-balancing compounds into your existing habits, helping to support mental clarity and relaxation.
Choosing the Right Adaptogen Products
When it comes to adaptogens, quality matters. Start by looking for products that have undergone third-party testing and certification. These ensure that the product matches its label claims, giving you confidence in what you’re consuming. Opt for brands that provide clear ingredient details, including specific adaptogens and their dosages, rather than hiding behind vague "proprietary blends."
For example, research suggests that Ashwagandha is most effective when taken in doses of 300–600 mg per day. Look for products with clear labelling, including batch numbers and expiry dates, and ensure they comply with Food Standards Agency regulations for UK consumers.
Avoid products loaded with fillers, artificial additives, or unnecessary extras. If you’re new to adaptogens, it’s best to introduce them one at a time. This way, you can observe how your body reacts and determine which ones suit your needs best.
Pay close attention to the label for any contraindications, especially if you’re taking regular medications. Reputable manufacturers clearly state potential risks, making it easier for you to make informed choices.
Once you’ve selected a high-quality product, functional beverages offer a convenient and enjoyable way to incorporate adaptogens into your daily life.
Adaptogens in Functional Beverages
Functional beverages make it easy - and enjoyable - to include adaptogens in your routine. Take IMPOSSIBREW®'s Enhanced Lager and Pale Ale, for instance. These drinks feature a proprietary Social Blend™ that mimics the relaxing effects of traditional alcoholic beverages, but without the hangovers or other drawbacks.
These beverages are particularly appealing for busy professionals or parents looking to unwind while staying sharp for the next day. With less than 0.5% ABV, they’re a great alternative to alcohol. Plus, they cater to a variety of dietary needs, being vegan-friendly and gluten-free.
Timing is key when it comes to functional beverages. They work well as part of an evening wind-down routine or during social gatherings where you might otherwise reach for an alcoholic drink. Their unique blend supports relaxation without making you drowsy, helping to calm your mind while boosting alpha brain waves and serotonin levels.
While these drinks are convenient, it’s still important to be mindful of safety and potential interactions.
Safety Considerations
To get the most out of adaptogens, it’s essential to follow safe usage practices. Always consult your GP before starting adaptogens, especially if you’re pregnant, breastfeeding, or managing health conditions like autoimmune disorders. This is particularly important if you’re on medications such as immunosuppressants or psychiatric treatments.
Some adaptogens can interact with medications. For instance, Ashwagandha might affect thyroid medications, potentially leading to overstimulation. Other examples include interactions with blood pressure drugs, diabetes treatments, or blood thinners. A quick chat with your GP or pharmacist can help you understand any risks based on your current prescriptions.
During the first few weeks, keep an eye out for side effects like digestive discomfort, headaches, or allergic reactions. Starting with a low dose and gradually increasing can help your body adjust while minimising any adverse effects. If side effects persist, stop using the adaptogen and consult your healthcare provider. Keeping a simple journal to track your stress levels, sleep patterns, and overall wellbeing can also help you evaluate how well the adaptogens are working for you.
Since long-term safety data for many adaptogens is still limited, it’s a good idea to check in with your healthcare provider regularly, especially if you’re using multiple adaptogens at once.
Current Research Gaps and Future Studies
Our understanding of adaptogens is still far from complete, which makes it tough for both consumers and healthcare professionals to make well-informed decisions about their use.
One major issue is standardisation. Products labelled with the same adaptogen often differ significantly in terms of active compound levels, extraction techniques, and plant sources [6][8]. This lack of consistency makes it difficult to compare findings across studies or establish reliable dosing recommendations. A 2018 review highlighted that many adaptogen studies involved fewer than 100 participants and often lacked rigorous controls or blinding [6].
Another challenge stems from the fact that most current research is based on small-scale studies. Much of the evidence comes from animal research or limited human trials, which makes it hard to generalise findings [2][6][7]. For example, while studies on Rhodiola rosea have shown it can reduce stress markers like cortisol in animal models [4], these results haven’t been fully validated in large human trials. The small sample sizes contribute to the incomplete picture of how adaptogens work.
The mechanisms of adaptogen action are also not fully understood [2][3][4]. Without a clearer understanding, it’s difficult to predict which adaptogens might be most effective for specific individuals or conditions.
There are also gaps in safety data, especially when it comes to long-term or high-dose use. Comprehensive studies on these aspects are still lacking [5][7]. Adding to the complexity is the placebo effect, where perceived benefits might stem more from participants’ expectations than the adaptogens themselves [6][7]. More rigorous trials are needed to distinguish genuine effects from psychological ones.
Another hurdle is measurement inconsistency. There’s no universally accepted method for assessing stress levels or cognitive performance, which complicates research efforts [6].
Looking ahead, future research should prioritise large-scale, randomised controlled trials involving diverse populations. Studies comparing single adaptogens to combinations, as well as research into their effects on specific cognitive functions and stress biomarkers, are also crucial [2][3][6]. Additionally, exploring how adaptogens perform in functional beverages - like those developed by IMPOSSIBREW® - offers potential for understanding their role in mental health within everyday settings [4].
The growing consumer interest in adaptogens has driven market expansion, but the research has not kept pace. This creates a gap between marketing claims and evidence-based recommendations [5][6][7]. Bridging this gap will require more rigorous studies to confirm benefits and establish safety guidelines, especially for products like enhanced non-alcoholic beverages, which are gaining popularity.
Regulatory bodies like the Medicines and Healthcare products Regulatory Agency (MHRA) play a key role in shaping the future of adaptogen research and product development. Their oversight ensures products are backed by strong evidence and protects consumers from misleading claims or unsafe formulations [6][7]. Addressing these gaps will provide clearer guidance for consumers and support the development of functional beverages, such as those offered by IMPOSSIBREW®.
Conclusion: Using Adaptogens for Better Health
Adaptogens present a natural way to manage stress and sharpen focus, backed by scientific research and centuries of traditional use. These plant-derived substances help regulate the body's stress response, offering an alternative to conventional methods of stress management.
Studies have shown that certain adaptogens can reduce fatigue, improve attention, and enhance mental endurance [2][4]. Unlike stimulants, which provide temporary energy bursts, adaptogens work gradually to balance the body's stress systems while supporting cognitive function over time.
Incorporating adaptogens into daily life has become more accessible than ever. From traditional herbal teas and supplements to modern functional beverages like those from IMPOSSIBREW®, there are plenty of options to suit different preferences. For example, enhanced non-alcoholic beers now allow you to enjoy adaptogenic benefits in social settings without compromising on taste or convenience.
For those looking for natural ways to relieve stress and improve mental clarity, adaptogens offer several advantages. They have been shown to provide neuroprotective, anti-fatigue, and anxiety-reducing effects without the side effects often linked to pharmaceutical options [2][3]. Research also suggests they can boost alpha brain waves and serotonin levels, promoting a calm yet focused state of mind while supporting mood balance [1].
Beyond stress relief, adaptogens have been associated with improved mental performance, greater physical stamina, and quicker recovery from both mental and physical challenges [2][4]. These benefits make them particularly appealing to busy professionals, students, and anyone dealing with high levels of stress or demanding schedules.
However, as with any wellness supplement, it's essential to choose high-quality products from trusted sources. If you have existing health conditions or take medications, consulting a healthcare professional is a wise step [7][8]. Starting with well-researched adaptogens and observing how your body responds can help you make the most of their potential.
As more research unfolds, adaptogens continue to blend ancient practices with modern health needs, offering a natural way to build resilience and maintain balance in today's hectic world.
FAQs
How are adaptogens different from caffeine when it comes to managing stress and improving focus?
Adaptogens and caffeine take very different approaches when it comes to managing stress and boosting focus. Caffeine is a stimulant that offers a quick energy lift by increasing alertness and temporarily masking fatigue. On the other hand, adaptogens are natural compounds that help the body adjust to stress gradually. Instead of giving an instant jolt, they support the adrenal system and encourage long-term balance.
Research indicates that adaptogens like ashwagandha and rhodiola can enhance focus and resilience by lowering cortisol levels and promoting mental clarity. Unlike caffeine, which can sometimes cause jitters or lead to energy crashes, adaptogens provide a calm yet energising effect - ideal for maintaining steady mental performance throughout the day.
Adding adaptogens to your routine is simple. You can explore teas, supplements, or even innovative options like IMPOSSIBREW®. This unique product infuses adaptogens into non-alcoholic beers, offering a relaxing and refreshing way to enjoy their benefits.
Are adaptogens safe to use, and should people on medication take any precautions?
Adaptogens are widely regarded as safe for most people when used as instructed, but it's worth noting that individual experiences can differ. If you're on any medication, it’s a good idea to check with your GP or healthcare provider before adding adaptogens to your routine, as they might interact with specific prescriptions or medical conditions.
Side effects, when they occur, are usually mild. These might include digestive upset, headaches, or, in rare cases, allergic reactions. To reduce any potential risks, start with a small dose and observe how your body reacts. Also, make sure to opt for high-quality products from trusted sources to ensure both safety and reliability.
What scientific evidence supports the use of adaptogens for reducing stress and improving focus?
Adaptogens are natural compounds, typically derived from plants, believed to help the body manage stress and maintain a sense of balance. Research indicates that certain adaptogens, like ashwagandha, rhodiola, and ginseng, may play a role in reducing cortisol levels - commonly known as the stress hormone - and enhancing mental clarity by aiding brain function and energy regulation.
Take rhodiola, for instance. Studies suggest it can help combat fatigue and improve focus, especially during stressful times. Similarly, ashwagandha has been examined for its potential to lower stress levels and sharpen concentration by influencing how the body responds to stress. While further studies are needed, the current evidence points to adaptogens as a promising option for stress management and improved focus.
If you're looking to add adaptogens to your daily life, you might explore supplements, teas, or functional drinks enriched with these ingredients. For example, IMPOSSIBREW® offers non-alcoholic beers infused with adaptogens, providing a relaxing and enjoyable way to support your overall well-being.
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What is IMPOSSIBREW®?
IMPOSSIBREW® is a pioneering non-alcoholic beer brand based in the UK that aims to create the world's most complete alcohol alternative using patent-pending technology.
Founded by Mark Wong in 2021 and working with some of the world's best professors, scientists and expert brewers, IMPOSSIBREW® specialises in expertly crafted non-alcoholic beers designed to match full ABV beers in both taste and feeling.
Product Range
IMPOSSIBREW® offers a range of enhanced non-alcoholic beers, including:
- Enhanced Lager (0.5% ABV)
- Enhanced Pale Ale (0.5% ABV)
- Limited Editions (Seasonal)
Key Benefits
The key feature that sets IMPOSSIBREW® apart is its proprietary "Social Blend™" - a combination of active botanical ingredients and nootropics using patent-pending technology* designed to recreate the relaxing effects of alcohol without the negative side effects.
Along with record-breaking quality flavour that comes from a unique process without removing alcohol.
Social Blend™ Ingredients
Developed with leading scientists in top UK universities, Social Blend™ includes:
- L-Theanine
- Ashwaghanda
- Soluble Plant Fibres
- Vitamin B1
- Various Plant Extracts.
These ingredients are chosen for their potential to boost serotonin, promote relaxation, and create a calming effect similar to the "one or two pint feeling" without hangovers.
See more details on our very own research paper, with over 1,000 participants:
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IMPOSSIBREW® has received several notable achievements:
- Featured on BBC's Dragons' Den
- Awarded the first and only Gold Medal in the No/Low beer category from the London Beer Competition
- Received multiple industry Gold awards in categories against Full-ABV beers
- Most followed No/Low Alcohol brand on TikTok globally.
Mission and Vision
IMPOSSIBREW® is on a mission to redefine non-alcoholic drinking by creating better-than-alcohol alternatives for those who love beer but want to avoid the health risks associated with alcohol consumption.
The company aims to become the global leading alcohol alternative brand, focusing on helping people transition to a healthier mode of relaxation without the traditional issues and side effects of alcohol.
Production and Ingredients
IMPOSSIBREW® combines traditional brewing methods with their proprietary Social Blend™ along with patent-pending technology*
The beers are made with traditional brewing ingredients such as water, malted barley, wheat, hops, and yeast, in addition to the Social Blend™ components - leveraging their unique cryogenic fermentation process, which means no alcohol is ever removed from the product - ensuring the most authentic quality taste you've come to expect.
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IMPOSSIBREW® caters to consumers who:
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*Patent pending in the UK under application number GB2415685.3
How does 'Social Blend™' work?
Social Blend™ is our proprietary alcohol alternative made from a blend of science-backed ingredients using patent-pending technology*.
Designed to replicate the sensory and social relaxing experience of drinking, minus the headaches (and bad decisions).
Developed with Dr Paul Chazot, Bioscience Professor and Chair of Pharmacology at Durham University.
Key Components and Mechanisms
- L-Theanine:
- Ashwagandha Root:
- Vitamin B1 (Thiamine):
- Various nootropic herbs:
Benefits
- Relaxation: The blend promotes a state of relaxation without the sedative effects typically associated with alcohol.
- Mental Calm: By boosting alpha brain waves and serotonin levels, it helps maintain a calm and focused mental state.
- Stress Relief: The combination of L-Theanine, Ashwagandha, and Vitamin B1 helps mitigate stress and anxiety.
- Mood Enhancement: The inclusion these ingredients and other botanicals supports mood regulation and overall positive outlook.
IMPOSSIBREW®'s Social Blend™ is a carefully crafted combination of nootropic and adaptogenic ingredients designed to offer a relaxing and mood-enhancing experience without the drawbacks of alcohol. It leverages the natural properties of its components to promote relaxation, reduce stress, and enhance mood, making it a unique alternative to traditional alcoholic beverages.
(Read our latest research paper here)
*Patent pending in the UK under application number GB2415685.3
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How is 0.5% ABV alcohol-free?
Yes, we know it's confusing. Isn't 0.5% ABV still alcoholic? Officially, 0.5% ABV is classified as Dealcoholised.
- In fact, most things we consume daily have more than 0.5% ABV
- Burger Rolls - 1.2% ABV
- Orange Juice - 0.5% ABV
- Ripe Banana - 0.5% ABV
After more than 2 years of research, we've found that the 0.5% ABV from our natural brewing process significantly increases both flavour and mouthfeel - without spiking your blood alcohol level (BAC).
Is it really gluten-free?
Yes, IMPOSSIBREW® Enhanced Lager is gluten-free. Even though it contains wheat and barley, our beers have been third-party tested to contain less than 10 parts per million (PPM) of gluten, which meets the criteria to be listed as, and labeled gluten-free.
Does it have alcohol tax?
No. While it is true that our beers don't contain alcohol, and thus don't incur UK alcohol duty, we'd like to highlight some factors here that might be helpful in reflecting the value we provide.
- One-to-One Brewing Process: At IMPOSSIBREW, we take pride in our unique brewing techniques. Unlike other non-alcoholic beers, our products are never diluted, watered-down, or have their alcohol content removed - and some even dilute their alcoholic beers up to 5x. This means that our brewing process involves the same level of craftsmanship, time, and resources as a traditional craft beer, resulting in comparable production costs.
- Effective Nootropics: In our commitment to creating the most relaxing non-alcoholic beers, we utilise only the highest quality nootropics as our active ingredients, in safe and effectives dosages. At current alcohol tax rates for a 5% ABV beer, the cost of our nootropics more than double that. Instead of contributing the amounts as tax, why not have it contribute to the product quality itself?
- Small Scale Brewing: Currently, we operate on a smaller scale, which makes us less competitive than large, commercial brewers (often +10,000x our brewing size). As a growing business, we are passionate about our mission to create unique, high-quality non-alcoholic experiences, and we truly appreciate your support. As we continue to grow and expand our production capabilities, we look forward to passing on even more savings to our valued community!
At IMPOSSIBREW, we prioritise offering our customers an enhanced, premium, non-alcoholic beer experience by combining innovative brewing techniques, quality active nootropic ingredients, and award-winning taste. While our pricing may differ from other non-alcoholic competitors, we believe that the value proposition and unique experience our beers provide are well worth it.
At the end of the day, tasting is believing. So give it a try and let us know what you think - risk-free with our IMPOSSIBREW® Guarantee.
Who shouldn't drink IMPOSSIBREW®?
It is not recommended for pregnant or breastfeeding women, those with certain medical conditions like GI disorders or hypertension, or individuals taking specific medications such as antidepressants, immunosuppressants or blood thinners. If you fall into any of these categories, it's best to consult with your doctor first.
Ashwagandha can lead to overstimulation (i.e. restlessness) if taken alongside thyroid medication.
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For thousands of years, we had only one way to unwind together. One way to let our guards down. One way to bridge the gap between who we are and who we are with others.
Not because it was perfect. But because it was all we had.
We decided that wasn't good enough.
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Where being present with others doesn't mean being absent from yourself. Where letting go doesn't mean losing control.This isn't about removing alcohol. This is about something better.
Our Social Blend™ technology isn't an accident. It's the result of questioning everything we thought we knew about social drinking. About working with scientists to understand what we're really seeking in these moments of connection. About daring to imagine something that wasn't possible before.
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