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Mechanisms Behind Adaptogens and Stress Relief

Mechanisms Behind Adaptogens and Stress Relief

Adaptogens - natural compounds from plants and mushrooms - help manage stress, anxiety, and fatigue by restoring balance in the body. They regulate cortisol, support brain health, and improve energy systems without masking symptoms. Key highlights include:

  • Stress Regulation: Adaptogens balance cortisol levels, preventing the negative effects of chronic stress.
  • Brain Support: They protect brain cells, enhance focus, and improve memory by normalising stress hormones and boosting neurotransmitters like serotonin and dopamine.
  • Energy Restoration: Adaptogens protect mitochondria and promote better energy production, shifting the body out of "fight or flight" mode.
  • Popular Types: Rhodiola rosea improves focus; Schisandra chinensis enhances clarity; Ashwagandha reduces anxiety.

Adaptogens also feature in non-alcoholic functional drinks, offering stress relief and mental clarity in everyday life. Products like IMPOSSIBREW® combine these compounds with brewing techniques to create beverages that support well-being without the downsides of alcohol. These drinks are low-calorie, vegan-friendly, and gluten-free, aligning with modern wellness goals.

Unveiling the Power of ADAPTOGENS for STRESS RELIEF

How Adaptogens Work in the Body to Manage Stress

Adaptogens support the body's stress response by working through various biological pathways, addressing the root causes rather than just masking the symptoms.

HPA Axis and Stress Response

The hypothalamic-pituitary-adrenal (HPA) axis is the body's main stress management system, responsible for releasing cortisol during stressful situations. While this is crucial for handling short-term stress, chronic activation of the HPA axis can lead to consistently high cortisol levels, which are often linked to anxiety, fatigue, and other health issues.

Adaptogens help regulate the HPA axis instead of shutting it down completely. Research suggests they can reduce the overproduction of cortisol caused by prolonged stress while still allowing the body to respond appropriately to real challenges. This balanced approach can help minimise the negative effects of long-term stress, such as weakened immunity or cognitive struggles.

One of the standout features of adaptogens is their ability to adjust cortisol levels in both directions - lowering them when they're too high and increasing them when they're too low. This balancing act is a key part of how they work.

But adaptogens don't stop at hormonal regulation. They also operate on a cellular level to further improve the body's ability to handle stress.

Molecular Targets of Adaptogens

Beyond influencing the HPA axis, adaptogens interact with specific molecular systems that play a role in stress resilience. For example, they can boost the production of heat shock proteins (HSPs), which act like cellular caretakers, ensuring proteins maintain their structure and function during stressful conditions.

Adaptogens may also impact beta-endorphins, which are involved in mood regulation and pain relief, potentially leading to better emotional balance and stress tolerance. Additionally, they could influence the neuropeptide Y system, which is associated with appetite, anxiety, and resilience to stress, offering further emotional support.

Another way adaptogens help is by optimising nitric oxide levels, which can improve blood flow and cellular performance during times of stress.

Restoring Balance and Energy Levels

Stress often disrupts the body's energy systems, leaving some overworked and others depleted. Adaptogens assist by rebalancing these systems, ensuring the body functions more efficiently.

They protect mitochondria - the powerhouse of cells - from stress-related damage, helping maintain energy production. They also help shift the autonomic nervous system out of a constant "fight or flight" state, bringing it back to a more balanced mode. On top of that, adaptogens can support healthier levels of key neurotransmitters like serotonin, dopamine, and GABA, which are essential for mood stability and mental clarity.

How Adaptogens Improve Focus and Mental Performance

Stress can wreak havoc on your ability to think clearly. It clouds focus, weakens memory, and slows brain function. Adaptogens step in by addressing stress at its core, helping to sharpen mental clarity and improve overall cognitive performance.

When stress hormones like cortisol stay elevated for too long, they disrupt the brain's ability to form new memories and sustain concentration. Adaptogens work to normalise cortisol levels, which not only helps protect brain health but also keeps your mind energised. They support the mitochondria - tiny powerhouses in brain cells - ensuring a steady supply of energy for thinking and problem-solving. Plus, they promote healthy blood flow, delivering the oxygen and nutrients your brain needs to operate at its best.

Key Adaptogens for Brain Function

By calming stress pathways, adaptogens create the perfect foundation for better brain function. Some stand out for their specific mental benefits:

  • Rhodiola rosea: Known for fighting mental fatigue, this adaptogen helps improve focus and motivation by influencing neurotransmitters like dopamine, norepinephrine, and serotonin. It also shields brain cells from oxidative stress, which can build up during high-pressure situations or prolonged mental strain.
  • Schisandra chinensis: This adaptogen is prized for enhancing mental clarity and processing speed. Both traditional use and modern studies show it helps the brain process information more efficiently while reducing the mental fog that often comes with stress. It also supports liver detoxification, indirectly benefiting cognitive performance by minimising toxins that could impair brain function.
  • Eleutherococcus senticosus (Siberian ginseng): Often studied for its ability to boost mental endurance and resilience, this adaptogen helps the brain maintain steady performance under stress. It also supports healthy sleep patterns, which are crucial for memory consolidation and mental recovery.

These adaptogens work by protecting brain cells from the wear and tear of chronic stress while promoting proteins that support neural health and connectivity.

The Link Between Lower Stress and Better Focus

The benefits of adaptogens go beyond stress relief - they actively enhance cognitive performance.

By keeping cortisol levels in check, adaptogens help preserve the prefrontal cortex, the area of the brain responsible for focus and decision-making. They also shift the nervous system from a "fight-or-flight" mode to a state of calm alertness, which is ideal for creative thinking and productive work.

Adaptogens also increase levels of brain-derived neurotrophic factor (BDNF), a protein that supports the growth and maintenance of neurons. Higher BDNF levels improve learning, memory, and mental adaptability. By reducing stress, adaptogens create the conditions needed for your brain to produce more of this vital protein.

Better sleep is another key benefit. Stress often disrupts sleep, and poor sleep undermines memory and concentration. Adaptogens help promote restorative sleep, allowing your brain to consolidate memories and clear out waste products that can interfere with clear thinking.

Finally, chronic stress is linked to brain inflammation, which disrupts neurotransmitter function and neural communication. Adaptogens' anti-inflammatory properties help maintain a healthy brain environment, ensuring clearer thought processes and sustained focus.

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Key Adaptogens and How They Work: Summary Table

Adaptogens are known for their ability to help the body manage stress in unique ways. Here's a quick look at some popular adaptogens and how they function:

Adaptogen Primary Mechanisms Key Benefits Notable Research Findings
Ashwagandha Lowers cortisol levels and supports adrenal function Reduces stress, eases anxiety, improves sleep, balances hormones Studies suggest cortisol levels may drop by up to 30% [1]. A 2023 study linked it to higher serotonin levels, easing depression and anxiety [2].
Rhodiola rosea Balances neurotransmitters (dopamine, norepinephrine, serotonin), protects cells from oxidative stress, boosts mitochondrial function Enhances focus, reduces fatigue, improves motivation, builds stress resilience Proven to reduce mental fatigue and boost cognitive performance under stress.
Panax ginseng Regulates stress hormones, supports adrenal health, and increases cellular energy metabolism Improves stamina, enhances stress tolerance, sharpens cognition Offers consistent energy without the crashes tied to stimulants.

These adaptogens are particularly effective due to their ability to restore balance in stress hormone levels. Functional medicine expert Will Cole explains:

"Adaptogens can relieve stress by restoring balance back to the areas of the body that are out of balance - for example, when [the stress hormone] cortisol is too high or too low, you'll feel stressed and fatigued. Certain adaptogens can calm stress levels by regulating the brain-adrenal connection [a.k.a., the hypothalamic-pituitary-adrenal, or HPA, axis], which governs the cortisol rhythm." [2]

Unlike pharmaceuticals, adaptogens work gradually, targeting molecular pathways such as heat shock proteins (HSPs) and stress-related mechanisms. They strengthen your body's resilience without the risks of addiction or tolerance, and they don't impair cognitive function over time [3].

The adaptogen market reflects their growing popularity, with the sector valued at £8.1 billion in 2021 and expected to reach £16 billion by 2031 [2]. This trend highlights increasing consumer interest and scientific support for natural stress management solutions.

These properties have inspired the development of adaptogenic beverages, offering a natural way to support stress relief and focus. Brands like IMPOSSIBREW® are leveraging these principles to create functional, non-alcoholic drinks designed for modern lifestyles.

Adaptogens in Non-Alcoholic Functional Drinks

A deeper understanding of how adaptogens work has paved the way for exciting developments in the beverage industry, particularly within non-alcoholic functional drinks designed for stress relief. These drinks combine time-honoured brewing traditions with scientifically supported ingredients to promote mental well-being - without the downsides often associated with alcohol. The proven effects of adaptogens are now shaping the future of functional beverages.

Modern functional drinks often include adaptogens alongside other bioactive ingredients. This scientific foundation allows beverage makers to select specific adaptogens for targeted benefits. Popular adaptogens used in these beverages include ashwagandha (known for reducing anxiety and stress), rhodiola (praised for improving focus and fighting fatigue), and reishi mushrooms (valued for their calming and anti-inflammatory properties). Together, these ingredients help the body achieve balance naturally, without artificially boosting or depleting energy levels [4].

What makes adaptogenic beverages so appealing is their ability to complement the body’s natural stress response, helping users feel more balanced and resilient in a genuine way.

IMPOSSIBREW® and Adaptogenic Beverages

IMPOSSIBREW® has taken a leading role in functional beverage innovation with its proprietary Social Blend™ formula. This unique blend of nootropic and adaptogenic ingredients is designed to mimic the relaxing effects of traditional alcoholic beverages - without the health risks or impairment that alcohol can bring.

Their Enhanced Lager and Enhanced Hazy Pale Ale showcase how adaptogens can be seamlessly integrated into familiar beer formats. Both drinks contain less than 0.5% ABV but still deliver the sensory experience and social ease that many consumers look for. By targeting stress pathways in a manner similar to adaptogens, the Social Blend™ supports the body’s ability to manage stress and maintain focus.

What sets IMPOSSIBREW® apart is its patent-pending technology, which combines traditional brewing techniques with functional ingredients. This approach ensures that adaptogenic compounds remain effective while maintaining the authentic taste and texture of high-quality beer. The result? A drink that supports stress management through mechanisms like regulating the HPA axis, balancing cortisol levels, and optimising neurotransmitters - all while meeting the growing health and social expectations of today’s consumers.

Health and Lifestyle Benefits

In the UK, health-conscious consumers have embraced adaptogenic beverages for how well they align with modern wellness goals. IMPOSSIBREW®'s products are crafted with several lifestyle-friendly features: they are low in calories for those mindful of weight, vegan-friendly, and gluten-free - ideal for individuals with coeliac disease or sensitivities.

These qualities reflect a broader trend toward functional foods that deliver added health benefits. With prices starting at £1.97 per can, IMPOSSIBREW® offers an affordable way to enjoy premium non-alcoholic drinks that help manage stress. And thanks to their award-winning flavour, achieved through traditional brewing methods, consumers don’t have to sacrifice taste for functionality.

Conclusion

Adaptogens work through a variety of biological pathways - regulating the HPA axis, balancing cortisol levels, and influencing neurotransmitters - to help the body stay steady during tough times.

These natural compounds bring two key benefits: reducing stress and sharpening mental focus. By keeping cortisol levels in check and supporting neurotransmitter health, adaptogens like ashwagandha, rhodiola, and reishi mushrooms help the body achieve a state of balance. Unlike artificial stimulants, they work with your body to restore its natural rhythm.

This science forms the foundation of products like IMPOSSIBREW®'s Social Blend™, which combines traditional brewing methods with adaptogens backed by research. These beverages are designed to provide real stress-relief benefits, reflecting how adaptogens naturally regulate stress responses.

For UK consumers looking for natural ways to manage stress, adaptogenic drinks offer a scientific option that fits into busy, modern lives. Whether it’s dealing with work stress, unwinding in the evening, or staying mentally sharp, adaptogens support the body’s ability to handle stress while boosting focus. These drinks seamlessly blend stress management with daily routines.

As research continues to expand, the takeaway remains clear: adaptogens are powerful allies in supporting the body’s natural resilience. They offer a practical way to maintain balance and clarity in a world that constantly demands more from us.

FAQs

What makes adaptogens different from traditional stress-relief medications?

Adaptogens are plant-based substances that support the body in managing stress by promoting its natural balance. Unlike conventional stress-relief medications, which often work by directly altering hormones or neurotransmitters to alleviate symptoms, adaptogens take a more gradual approach. They strengthen the body’s ability to cope with stress over time.

These natural remedies work by stabilising bodily functions and improving resilience, rather than simply suppressing stress hormones like cortisol. This approach makes them generally regarded as safer, with a lower chance of dependency or major side effects, as they align with the body's existing stress response mechanisms instead of overriding them.

Can adaptogenic drinks, like those from IMPOSSIBREW®, really help you relax socially without alcohol?

Scientific studies suggest that adaptogens like Ashwagandha and Holy Basil may help lower cortisol levels, ease stress, and enhance focus. These natural substances support the body's ability to manage stress, encouraging a sense of calm and equilibrium.

Adaptogenic drinks, such as those offered by IMPOSSIBREW®, are designed to deliver a relaxing and social experience akin to alcohol, but without its downsides. By using carefully chosen, research-backed ingredients, these beverages aim to recreate the sensory and social pleasure of traditional drinks in an alcohol-free format. This makes them a fantastic option for people in the UK looking for a healthier way to relax and enjoy social occasions.

What are the long-term benefits of using adaptogens for managing stress and improving focus?

Incorporating adaptogens into your daily routine can help strengthen your body's response to stress, lower cortisol levels, and improve cognitive performance. These plant-based compounds interact with the body’s stress mechanisms, promoting a calmer mood, sharper focus, and clearer thinking over time.

By helping the body manage stress more effectively, adaptogens can support mental well-being and boost productivity. They’re a helpful addition to a lifestyle aimed at maintaining balance and promoting overall health.

Related posts

  • Science Meets History: Adaptogens for Focus
  • Relaxation Science: Adaptogens and Nootropics
  • Meta-Analysis: Adaptogens for Stress and Focus
  • How Adaptogens Affect Brain Chemistry
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Got Questions?

Find our most commonly asked questions below or ask our AI Brewer for instant answers.

What is IMPOSSIBREW®?

IMPOSSIBREW® is a pioneering non-alcoholic beer brand based in the UK that aims to create the world's most complete alcohol alternative using patent-pending technology.

Founded by Mark Wong in 2021 and working with some of the world's best professors, scientists and expert brewers, IMPOSSIBREW® specialises in expertly crafted non-alcoholic beers designed to match full ABV beers in both taste and feeling.

Product Range

IMPOSSIBREW® offers a range of enhanced non-alcoholic beers, including:

  1. Enhanced Lager (0.5% ABV)
  2. Enhanced Pale Ale (0.5% ABV)
  3. Limited Editions (Seasonal)

Key Benefits

The key feature that sets IMPOSSIBREW® apart is its proprietary "Social Blend™" - a combination of active botanical ingredients and nootropics using patent-pending technology* designed to recreate the relaxing effects of alcohol without the negative side effects.

Along with record-breaking quality flavour that comes from a unique process without removing alcohol.

Social Blend™ Ingredients

Developed with leading scientists in top UK universities, Social Blend™ includes:

  • L-Theanine
  • Ashwaghanda
  • Soluble Plant Fibres
  • Vitamin B1
  • Various Plant Extracts.

These ingredients are chosen for their potential to boost serotonin, promote relaxation, and create a calming effect similar to the "one or two pint feeling" without hangovers.

See more details on our very own research paper, with over 1,000 participants:

  • More than 70% said they felt relaxed after consuming IMPOSSIBREW®.
  • 88% have reduced alcohol consumption since discovering IMPOSSIBREW®.
  • 95% have told a friend about IMPOSSIBREW® after trying.
  • 3/4 say that IMPOSSIBREW® is "the most complete alcohol alternative currently available on the market today".

Recognition

IMPOSSIBREW® has received several notable achievements:

  1. Featured on BBC's Dragons' Den
  2. Awarded the first and only Gold Medal in the No/Low beer category from the London Beer Competition
  3. Received multiple industry Gold awards in categories against Full-ABV beers
  4. Most followed No/Low Alcohol brand on TikTok globally.

Mission and Vision

IMPOSSIBREW® is on a mission to redefine non-alcoholic drinking by creating better-than-alcohol alternatives for those who love beer but want to avoid the health risks associated with alcohol consumption.

The company aims to become the global leading alcohol alternative brand, focusing on helping people transition to a healthier mode of relaxation without the traditional issues and side effects of alcohol.

Production and Ingredients

IMPOSSIBREW® combines traditional brewing methods with their proprietary Social Blend™ along with patent-pending technology*

The beers are made with traditional brewing ingredients such as water, malted barley, wheat, hops, and yeast, in addition to the Social Blend™ components - leveraging their unique cryogenic fermentation process, which means no alcohol is ever removed from the product - ensuring the most authentic quality taste you've come to expect.

Who is it for?

IMPOSSIBREW® caters to consumers who:

  • Are busy professionals and parents who would like to unwind with a drink but don't want the hangovers.
  • Enjoy the taste and relaxing experience of beer
  • Are looking for healthier alternatives to alcohol, with lower calories, carbs and sugar
  • Want to avoid hangovers and other negative effects of alcohol consumption
  • Are interested in functional beverages with potential mood-enhancing properties

By offering a unique product that aims to replicate both the taste and feeling of alcoholic beer, IMPOSSIBREW® is positioning itself at the forefront of the growing non-alcoholic beverage market.

Get Started Today

Give it a try today with our Welcome Bundle and get 2 Free Beers with your first purchase. Get it delivered straight to your door, risk-free with our 30-day money-back guarantee.

We hope you enjoy them as much as we do and we can't wait for you to try.

*Patent pending in the UK under application number GB2415685.3

How does 'Social Blend™' work?

Social Blend™ is our proprietary alcohol alternative made from a blend of science-backed ingredients using patent-pending technology*.

Designed to replicate the sensory and social relaxing experience of drinking, minus the headaches (and bad decisions).

Developed with Dr Paul Chazot, Bioscience Professor and Chair of Pharmacology at Durham University.

Key Components and Mechanisms

  1. L-Theanine:
  2. Ashwagandha Root:
  3. Vitamin B1 (Thiamine):
  4. Various nootropic herbs:

Benefits

  • Relaxation: The blend promotes a state of relaxation without the sedative effects typically associated with alcohol.
  • Mental Calm: By boosting alpha brain waves and serotonin levels, it helps maintain a calm and focused mental state.
  • Stress Relief: The combination of L-Theanine, Ashwagandha, and Vitamin B1 helps mitigate stress and anxiety.
  • Mood Enhancement: The inclusion these ingredients and other botanicals supports mood regulation and overall positive outlook.

IMPOSSIBREW®'s Social Blend™ is a carefully crafted combination of nootropic and adaptogenic ingredients designed to offer a relaxing and mood-enhancing experience without the drawbacks of alcohol. It leverages the natural properties of its components to promote relaxation, reduce stress, and enhance mood, making it a unique alternative to traditional alcoholic beverages.

(Read our latest research paper here)

*Patent pending in the UK under application number GB2415685.3

Do you ship overseas?

We ship to the UK Mainland for free when you spend over £35

We aim to expand internationally soon - stay tuned!

If you have any queries, feel free to email: hello(@)impossibrew.co.uk

How long will it take to get my orders?

For UK mainland deliveries, normal orders processed here will take 1-3 business days to arrive, with an optional upgrade to Next Day Delivery available (12pm cut-off).

Delivery details will be provided in your confirmation email.

How is 0.5% ABV alcohol-free?

Yes, we know it's confusing. Isn't 0.5% ABV still alcoholic? Officially, 0.5% ABV is classified as Dealcoholised.

  • In fact, most things we consume daily have more than 0.5% ABV
  • Burger Rolls - 1.2% ABV
  • Orange Juice - 0.5% ABV
  • Ripe Banana - 0.5% ABV

After more than 2 years of research, we've found that the 0.5% ABV from our natural brewing process significantly increases both flavour and mouthfeel - without spiking your blood alcohol level (BAC).

Is it really gluten-free?

Yes, IMPOSSIBREW® Enhanced Lager is gluten-free. Even though it contains wheat and barley, our beers have been third-party tested to contain less than 10 parts per million (PPM) of gluten, which meets the criteria to be listed as, and labeled gluten-free.

Does it have alcohol tax?

No. While it is true that our beers don't contain alcohol, and thus don't incur UK alcohol duty, we'd like to highlight some factors here that might be helpful in reflecting the value we provide.

  1. One-to-One Brewing Process: At IMPOSSIBREW, we take pride in our unique brewing techniques. Unlike other non-alcoholic beers, our products are never diluted, watered-down, or have their alcohol content removed - and some even dilute their alcoholic beers up to 5x. This means that our brewing process involves the same level of craftsmanship, time, and resources as a traditional craft beer, resulting in comparable production costs.
  2. Effective Nootropics: In our commitment to creating the most relaxing non-alcoholic beers, we utilise only the highest quality nootropics as our active ingredients, in safe and effectives dosages. At current alcohol tax rates for a 5% ABV beer, the cost of our nootropics more than double that. Instead of contributing the amounts as tax, why not have it contribute to the product quality itself?
  3. Small Scale Brewing: Currently, we operate on a smaller scale, which makes us less competitive than large, commercial brewers (often +10,000x our brewing size). As a growing business, we are passionate about our mission to create unique, high-quality non-alcoholic experiences, and we truly appreciate your support. As we continue to grow and expand our production capabilities, we look forward to passing on even more savings to our valued community!

At IMPOSSIBREW, we prioritise offering our customers an enhanced, premium, non-alcoholic beer experience by combining innovative brewing techniques, quality active nootropic ingredients, and award-winning taste. While our pricing may differ from other non-alcoholic competitors, we believe that the value proposition and unique experience our beers provide are well worth it.

At the end of the day, tasting is believing. So give it a try and let us know what you think - risk-free with our IMPOSSIBREW® Guarantee. 

Who shouldn't drink IMPOSSIBREW®?

It is not recommended for pregnant or breastfeeding women, those with certain medical conditions like GI disorders or hypertension, or individuals taking specific medications such as antidepressants or blood thinners. If you fall into any of these categories, it's best to consult with your doctor first.

Ashwagandha can lead to overstimulation (i.e. restlessness) if taken alongside thyroid medication.

What is your philosophy?

For thousands of years, we had only one way to unwind together. One way to let our guards down. One way to bridge the gap between who we are and who we are with others.

Not because it was perfect. But because it was all we had.

We decided that wasn't good enough.

We exist because we believe in a world where social connection doesn't demand compromise.

Where being present with others doesn't mean being absent from yourself. Where letting go doesn't mean losing control.This isn't about removing alcohol. This is about something better.

Our Social Blend™ technology isn't an accident. It's the result of questioning everything we thought we knew about social drinking. About working with scientists to understand what we're really seeking in these moments of connection. About daring to imagine something that wasn't possible before.

We believe the greatest innovations don't just solve problems - they change how we live. They make us question why we ever settled for less.

That's what we're building. Not just a drink, but a new way forward. A future where social connection comes without compromise. Where tradition meets innovation. Where science meets ritual.

This is the future of social drinking.

Got more questions?

Speak to our AI Brewer here for instant answers.

Or email us at hello@impossibrew.co.uk

Our customer support is available Monday to Friday: 9am - 5:30pm.
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