How Adaptogens Affect Brain Chemistry

Adaptogens are plant-based substances that help your body manage stress and maintain balance. They interact with brain chemicals like serotonin, dopamine, and GABA, which influence mood, focus, and relaxation. This makes them helpful for reducing stress, improving mental clarity, and supporting emotional stability.
Key points:
- Stress Support: Adaptogens regulate cortisol levels, helping you stay calm under pressure.
- Neurotransmitter Effects: They influence brain chemicals to improve mood, energy, and focus.
- Functional Drinks: Non-alcoholic beers, like those by IMPOSSIBREW®, now include adaptogens for stress relief and mental clarity.
Modern products make it easier to include adaptogens in daily life, offering a natural way to support mental health without relying on synthetic solutions.
ADAPTOGENS EXPLAINED: Ginseng, Ashwagandha, Rhodiola + Science of Stress
How Adaptogens Affect Neurotransmitters and Brain Pathways
Adaptogens influence brain chemistry by helping the body manage stress and supporting mental clarity. Early research indicates that they interact with neurotransmitters and stress pathways, laying the groundwork for understanding their effects on mood and cognition.
Key Neurotransmitters Affected by Adaptogens
Adaptogens are believed to impact several neurotransmitters that play essential roles in mood, focus, and relaxation:
- Dopamine: Known as the "motivation" neurotransmitter, dopamine is linked to focus and reward. Studies suggest that Rhodiola rosea may help regulate dopamine levels, improving concentration and reducing fatigue.
- Serotonin: This neurotransmitter is crucial for mood balance and can be disrupted by stress. Ashwagandha appears to support balanced cortisol levels, creating conditions that may promote healthy serotonin activity.
- GABA (gamma-aminobutyric acid): As the brain's calming neurotransmitter, GABA fosters relaxation without sedation. Adaptogens like Holy basil have been shown to enhance GABA activity, potentially offering a natural alternative to some medications.
- Acetylcholine: Vital for memory and learning, acetylcholine is another focus of adaptogen research. For instance, Ginseng may support acetylcholine levels, contributing to better cognitive performance.
Stress Regulation via the HPA Axis
The hypothalamic-pituitary-adrenal (HPA) axis is central to how the body reacts to stress. When stress occurs, the hypothalamus releases CRH, which triggers ACTH-driven cortisol production. Chronic overactivation of this system can harm memory, immunity, and mood.
Adaptogens may help regulate the HPA axis. Research on Ashwagandha suggests it can moderate cortisol levels, helping reduce stress intensity. This balance is particularly important for coping with the constant pressures of modern life.
Cellular Pathways and Brain Function
Adaptogens don't just affect neurotransmitters - they also strengthen cellular systems that support brain health. Here are some key mechanisms:
- Heat Shock Proteins (HSPs): These proteins act like a repair crew, fixing cellular damage caused by stress. Studies on Rhodiola rosea suggest it may increase HSP activity, helping combat mental fatigue.
- Glucocorticoid Receptors: These receptors bind cortisol, the primary stress hormone. Chronic stress can make them less responsive, but adaptogens may help restore their function, improving the body's stress response.
- Mitochondrial Function: Brain cells need a lot of energy, and mitochondria are responsible for producing it. Adaptogens like Ginseng may support mitochondrial health by reducing oxidative stress and ensuring efficient energy production.
These cellular processes might help explain why some people report improved focus, memory, and mood when using adaptogens. Their effects on both brain chemistry and cellular resilience offer a fascinating area for further research.
The Science Behind Adaptogens: Cognitive and Mood Benefits
Research is shedding light on the potential of adaptogens to boost mental performance and emotional balance. These plant-based compounds are thought to aid mental clarity, enhance the ability to handle stress, and support overall brain health.
What Studies Reveal
By influencing neurotransmitters and cellular processes, adaptogens are being studied for their impact on cognitive function and mood. Early research suggests they may help combat physical and mental fatigue by improving how the body manages energy. Unlike a quick jolt of stimulation, the benefits seem to build gradually, helping to stabilise stress responses, which in turn can sharpen focus and improve decision-making over time.
Popular Adaptogens and Their Effects
- Rhodiola rosea: Known for its ability to enhance motivation and concentration during stressful situations, this adaptogen works by regulating neurotransmitter activity.
- Ashwagandha: Often linked to reducing stress markers, it has been shown to improve attention and processing speed, particularly in those dealing with chronic stress.
- Schisandra chinensis: This adaptogen is associated with improved mental endurance and better sustained attention.
- Ginseng: Research suggests it may aid memory and learning by influencing neurotransmitter systems.
The growing body of evidence highlights the potential long-term cognitive advantages of these adaptogens, making them a focus for further scientific exploration.
sbb-itb-a752bf8
How Adaptogens Work in Functional Beverages
Adding adaptogens to beverages is reshaping how we think about mental wellness and socialising. These natural compounds are blended into drinks that not only taste great but also support brain health, helping to maintain balance and resilience under stress.
Adaptogens in Non-Alcoholic Beers
Non-alcoholic beers are now tapping into adaptogen science to offer a unique way to manage stress. By infusing these brews with adaptogens, they directly influence the hypothalamic-pituitary-adrenal (HPA) axis - the system responsible for regulating the body's stress response. This helps the body better handle anxiety and fatigue, offering a calming effect without the need for alcohol [1].
Many of these beverages pair adaptogens with nootropics to create a powerful combination. Together, they not only help reduce stress but also enhance cognitive functions like memory, creativity, focus, and motivation. The result? A drink that provides both relaxation and a mental boost [1].
The IMPOSSIBREW® Example
A standout example of this approach is IMPOSSIBREW® and their innovative Social Blend™. Their Enhanced Lager and Enhanced Hazy Pale Ale showcase how adaptogens can be seamlessly integrated into non-alcoholic beers. These drinks are crafted to replicate the relaxing effects of traditional beers, but without the drawbacks of alcohol.
Each can contains less than 0.5% ABV, ensuring the benefits come entirely from the adaptogens. This solves a major challenge in the functional beverage market: delivering therapeutic effects while keeping the flavour familiar. IMPOSSIBREW®’s formulations are designed to enhance mental clarity and productivity while staying true to the taste of beer.
Combining traditional brewing methods with cutting-edge formulations, IMPOSSIBREW® has created award-winning beers that not only taste great but also support mood and cognitive health.
Consumer Benefits for UK Audiences
For people in the UK, these drinks offer practical lifestyle benefits. With a growing focus on health-conscious choices, adaptogen-infused beers cater perfectly to modern needs. They provide an easy way to enjoy functional nutrition without disrupting daily routines.
These beverages are particularly appealing for their ability to promote relaxation and improve mood without the hangovers or negative side effects that come with alcohol [1]. This makes them especially attractive to younger generations who are looking for healthier ways to socialise while staying connected to their social rituals.
Whether it’s unwinding after work, catching up with friends, or relaxing at home, these functional beers fit effortlessly into British social life. Plus, they offer long-term support for mental health, making them a smart choice for anyone looking to combine enjoyment with wellness.
Conclusion: The Potential of Adaptogens for Mental and Social Well-Being
Adaptogens are showing promise as natural tools to help the brain manage stress and maintain balance. By working at the cellular level, they influence neurotransmitters and pathways that shape our mental state, cognitive abilities, and overall well-being. This insight highlights how science-backed, natural solutions can seamlessly integrate into daily life and social settings.
Key Takeaways
Adaptogens provide a way to support brain chemistry without the downsides often associated with traditional methods. By modulating the HPA axis and regulating neurotransmitters, they help maintain mental balance.
Their inclusion in functional beverages marks an exciting step forward in accessible wellness. Take IMPOSSIBREW®'s Social Blend™, for example. It delivers adaptogens in familiar beer formats, like their Enhanced Lager and Enhanced Hazy Pale Ale, combining therapeutic benefits with the comfort of traditional social rituals.
This approach resonates with modern UK lifestyles. Whether it’s relaxing after a tough day at work or catching up with friends, adaptogen-infused drinks offer cognitive support while preserving the familiar experience of a pint. Research has shown that adaptogens can enhance focus, reduce fatigue, and stabilise mood - all without the negative effects of alcohol or synthetic alternatives. This makes them especially appealing to health-conscious individuals looking for sustainable ways to boost mental well-being.
As the benefits of adaptogens become clearer, the next wave of formulations is set to provide even more targeted support.
The Future of Adaptogens in Everyday Life
The growing research into adaptogens suggests that we’ve only scratched the surface of their potential. As new studies emerge, we can expect more refined formulations designed to address specific aspects of brain chemistry with greater precision.
The rise of functional beverages also signals a shift in how society views mental health. Products like IMPOSSIBREW® show how wellness can be seamlessly woven into daily routines, making it easier for people to incorporate mental health support into their lives. This integration could lead to better long-term outcomes for resilience and emotional balance.
In the UK, this evolution aligns with changing attitudes towards alcohol and wellness. Younger generations are increasingly prioritising health without wanting to lose the social connections tied to traditional drinking. Adaptogen-enhanced beverages offer a practical solution that bridges these needs.
Looking ahead, adaptogens are likely to play a larger role in enhancing both work performance and social well-being. As our understanding of brain chemistry grows, future products could provide targeted support for challenges like workplace stress or social anxiety.
FAQs
How do adaptogens compare to traditional methods for managing stress?
Adaptogens are plant-based substances thought to help the body manage stress by balancing cortisol levels and promoting resilience. Some research indicates they might enhance mental focus, combat fatigue, and even offer protective benefits for the brain, making them an interesting option for managing stress.
Unlike traditional methods such as medication or therapy, adaptogens are often seen as having fewer side effects and being gentler on the body. That said, while initial findings are promising, more in-depth studies are needed to fully understand their long-term safety and effectiveness compared to conventional treatments. It's always a good idea to check with a healthcare professional before adding new supplements to your routine.
Is it safe to take adaptogens alongside other supplements or medications that impact brain chemistry?
Adaptogens are considered safe for most healthy adults, but mixing them with other supplements or medications that influence brain chemistry can occasionally cause interactions. For instance, they might affect how certain antidepressants or hormone-related supplements, such as maca or DHEA, function in the body. This interaction could potentially impact hormone levels or mood.
To minimise the risk of unexpected side effects or interactions, it’s wise to consult a healthcare professional before combining adaptogens with other substances that affect the brain. This way, you can ensure a tailored approach to your health and well-being.
What are the long-term effects of consuming adaptogen-infused drinks on mental health and brain function?
Regularly enjoying drinks infused with adaptogens could play a role in supporting mental well-being and brain function. These beverages are thought to help lower stress, lift your mood, and may even provide protection for brain health. Over time, they might aid in sharpening focus, boosting memory, and helping you handle daily stress more effectively.
That said, adaptogens can influence hormones, so overuse or improper consumption might lead to issues like hormonal imbalances or mood swings. Paying attention to how your body reacts and seeking advice from a healthcare professional, if needed, is always a wise approach.
When incorporated thoughtfully, adaptogen-based drinks might become a helpful part of your daily routine, encouraging a calmer, more focused mindset.
Related posts
Reading next
Got Questions?
Find our most commonly asked questions below or ask our AI Brewer for instant answers.
What is IMPOSSIBREW®?
IMPOSSIBREW® is a pioneering non-alcoholic beer brand based in the UK that aims to create the world's most complete alcohol alternative using patent-pending technology.
Founded by Mark Wong in 2021 and working with some of the world's best professors, scientists and expert brewers, IMPOSSIBREW® specialises in expertly crafted non-alcoholic beers designed to match full ABV beers in both taste and feeling.
Product Range
IMPOSSIBREW® offers a range of enhanced non-alcoholic beers, including:
- Enhanced Lager (0.5% ABV)
- Enhanced Pale Ale (0.5% ABV)
- Limited Editions (Seasonal)
Key Benefits
The key feature that sets IMPOSSIBREW® apart is its proprietary "Social Blend™" - a combination of active botanical ingredients and nootropics using patent-pending technology* designed to recreate the relaxing effects of alcohol without the negative side effects.
Along with record-breaking quality flavour that comes from a unique process without removing alcohol.
Social Blend™ Ingredients
Developed with leading scientists in top UK universities, Social Blend™ includes:
- L-Theanine
- Ashwaghanda
- Soluble Plant Fibres
- Vitamin B1
- Various Plant Extracts.
These ingredients are chosen for their potential to boost serotonin, promote relaxation, and create a calming effect similar to the "one or two pint feeling" without hangovers.
See more details on our very own research paper, with over 1,000 participants:
- More than 70% said they felt relaxed after consuming IMPOSSIBREW®.
- 88% have reduced alcohol consumption since discovering IMPOSSIBREW®.
- 95% have told a friend about IMPOSSIBREW® after trying.
- 3/4 say that IMPOSSIBREW® is "the most complete alcohol alternative currently available on the market today".
Recognition
IMPOSSIBREW® has received several notable achievements:
- Featured on BBC's Dragons' Den
- Awarded the first and only Gold Medal in the No/Low beer category from the London Beer Competition
- Received multiple industry Gold awards in categories against Full-ABV beers
- Most followed No/Low Alcohol brand on TikTok globally.
Mission and Vision
IMPOSSIBREW® is on a mission to redefine non-alcoholic drinking by creating better-than-alcohol alternatives for those who love beer but want to avoid the health risks associated with alcohol consumption.
The company aims to become the global leading alcohol alternative brand, focusing on helping people transition to a healthier mode of relaxation without the traditional issues and side effects of alcohol.
Production and Ingredients
IMPOSSIBREW® combines traditional brewing methods with their proprietary Social Blend™ along with patent-pending technology*
The beers are made with traditional brewing ingredients such as water, malted barley, wheat, hops, and yeast, in addition to the Social Blend™ components - leveraging their unique cryogenic fermentation process, which means no alcohol is ever removed from the product - ensuring the most authentic quality taste you've come to expect.
Who is it for?
IMPOSSIBREW® caters to consumers who:
- Are busy professionals and parents who would like to unwind with a drink but don't want the hangovers.
- Enjoy the taste and relaxing experience of beer
- Are looking for healthier alternatives to alcohol, with lower calories, carbs and sugar
- Want to avoid hangovers and other negative effects of alcohol consumption
- Are interested in functional beverages with potential mood-enhancing properties
By offering a unique product that aims to replicate both the taste and feeling of alcoholic beer, IMPOSSIBREW® is positioning itself at the forefront of the growing non-alcoholic beverage market.
Get Started Today
Give it a try today with our Welcome Bundle and get 2 Free Beers with your first purchase. Get it delivered straight to your door, risk-free with our 30-day money-back guarantee.
We hope you enjoy them as much as we do and we can't wait for you to try.
*Patent pending in the UK under application number GB2415685.3
How does 'Social Blend™' work?
Social Blend™ is our proprietary alcohol alternative made from a blend of science-backed ingredients using patent-pending technology*.
Designed to replicate the sensory and social relaxing experience of drinking, minus the headaches (and bad decisions).
Developed with Dr Paul Chazot, Bioscience Professor and Chair of Pharmacology at Durham University.
Key Components and Mechanisms
- L-Theanine:
- Ashwagandha Root:
- Vitamin B1 (Thiamine):
- Various nootropic herbs:
Benefits
- Relaxation: The blend promotes a state of relaxation without the sedative effects typically associated with alcohol.
- Mental Calm: By boosting alpha brain waves and serotonin levels, it helps maintain a calm and focused mental state.
- Stress Relief: The combination of L-Theanine, Ashwagandha, and Vitamin B1 helps mitigate stress and anxiety.
- Mood Enhancement: The inclusion these ingredients and other botanicals supports mood regulation and overall positive outlook.
IMPOSSIBREW®'s Social Blend™ is a carefully crafted combination of nootropic and adaptogenic ingredients designed to offer a relaxing and mood-enhancing experience without the drawbacks of alcohol. It leverages the natural properties of its components to promote relaxation, reduce stress, and enhance mood, making it a unique alternative to traditional alcoholic beverages.
(Read our latest research paper here)
*Patent pending in the UK under application number GB2415685.3
Do you ship overseas?
We ship to the UK Mainland for free when you spend over £35
We aim to expand internationally soon - stay tuned!
If you have any queries, feel free to email: hello(@)impossibrew.co.uk
How long will it take to get my orders?
For UK mainland deliveries, normal orders processed here will take 1-3 business days to arrive, with an optional upgrade to Next Day Delivery available (12pm cut-off).
Delivery details will be provided in your confirmation email.
How is 0.5% ABV alcohol-free?
Yes, we know it's confusing. Isn't 0.5% ABV still alcoholic? Officially, 0.5% ABV is classified as Dealcoholised.
- In fact, most things we consume daily have more than 0.5% ABV
- Burger Rolls - 1.2% ABV
- Orange Juice - 0.5% ABV
- Ripe Banana - 0.5% ABV
After more than 2 years of research, we've found that the 0.5% ABV from our natural brewing process significantly increases both flavour and mouthfeel - without spiking your blood alcohol level (BAC).
Is it really gluten-free?
Yes, IMPOSSIBREW® Enhanced Lager is gluten-free. Even though it contains wheat and barley, our beers have been third-party tested to contain less than 10 parts per million (PPM) of gluten, which meets the criteria to be listed as, and labeled gluten-free.
Does it have alcohol tax?
No. While it is true that our beers don't contain alcohol, and thus don't incur UK alcohol duty, we'd like to highlight some factors here that might be helpful in reflecting the value we provide.
- One-to-One Brewing Process: At IMPOSSIBREW, we take pride in our unique brewing techniques. Unlike other non-alcoholic beers, our products are never diluted, watered-down, or have their alcohol content removed - and some even dilute their alcoholic beers up to 5x. This means that our brewing process involves the same level of craftsmanship, time, and resources as a traditional craft beer, resulting in comparable production costs.
- Effective Nootropics: In our commitment to creating the most relaxing non-alcoholic beers, we utilise only the highest quality nootropics as our active ingredients, in safe and effectives dosages. At current alcohol tax rates for a 5% ABV beer, the cost of our nootropics more than double that. Instead of contributing the amounts as tax, why not have it contribute to the product quality itself?
- Small Scale Brewing: Currently, we operate on a smaller scale, which makes us less competitive than large, commercial brewers (often +10,000x our brewing size). As a growing business, we are passionate about our mission to create unique, high-quality non-alcoholic experiences, and we truly appreciate your support. As we continue to grow and expand our production capabilities, we look forward to passing on even more savings to our valued community!
At IMPOSSIBREW, we prioritise offering our customers an enhanced, premium, non-alcoholic beer experience by combining innovative brewing techniques, quality active nootropic ingredients, and award-winning taste. While our pricing may differ from other non-alcoholic competitors, we believe that the value proposition and unique experience our beers provide are well worth it.
At the end of the day, tasting is believing. So give it a try and let us know what you think - risk-free with our IMPOSSIBREW® Guarantee.
Who shouldn't drink IMPOSSIBREW®?
It is not recommended for pregnant or breastfeeding women, those with certain medical conditions like GI disorders or hypertension, or individuals taking specific medications such as antidepressants or blood thinners. If you fall into any of these categories, it's best to consult with your doctor first.
Ashwagandha can lead to overstimulation (i.e. restlessness) if taken alongside thyroid medication.
What is your philosophy?
For thousands of years, we had only one way to unwind together. One way to let our guards down. One way to bridge the gap between who we are and who we are with others.
Not because it was perfect. But because it was all we had.
We decided that wasn't good enough.
We exist because we believe in a world where social connection doesn't demand compromise.
Where being present with others doesn't mean being absent from yourself. Where letting go doesn't mean losing control.This isn't about removing alcohol. This is about something better.
Our Social Blend™ technology isn't an accident. It's the result of questioning everything we thought we knew about social drinking. About working with scientists to understand what we're really seeking in these moments of connection. About daring to imagine something that wasn't possible before.
We believe the greatest innovations don't just solve problems - they change how we live. They make us question why we ever settled for less.
That's what we're building. Not just a drink, but a new way forward. A future where social connection comes without compromise. Where tradition meets innovation. Where science meets ritual.
This is the future of social drinking.