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Bioavailability in Functional Beers: Key Factors
Functional beers are gaining popularity, but not all their health benefits are absorbed by your body. Bioavailability - how well your body absorbs nutrients - is the key. This article breaks down what impacts bioavailability and how brewing techniques, ingredient choices, and even your body chemistry play a role.
Key Takeaways:
- Brewing Process: Timing and temperature during brewing affect nutrient extraction. For example, wort boiling boosts phenolic content by 37.09%.
- Ingredients Matter: Compounds like xanthohumol and isoxanthohumol are naturally found in hops but require advanced brewing methods to improve absorption.
- Your Body Chemistry: Factors like weight, gender, and gut bacteria determine how much your body absorbs. For instance, certain bacteria can convert hop compounds into highly absorbable forms.
- Tech Innovations: Brands like IMPOSSIBREW® use proprietary tech (e.g., Social Blend™) to optimize ingredient absorption and improve effects like relaxation.
Quick Tips for Choosing Functional Beers:
- Look for beers with clear ingredient labels and brewing details.
- Opt for products that use advanced brewing techniques for better absorption.
- Consider your own body’s response - absorption varies for everyone.
Functional beers are more than just a trend. With the right brewing methods and ingredients, they can deliver real health benefits. Dive deeper to learn how it all works.
Factors Affecting Bioavailability
Brewing Process Effects
The brewing process plays a key role in how ingredients are absorbed. Factors like wort boiling, temperature, and timing significantly influence this. Phenolic compounds, mainly extracted from barley malt (70%) and hops (30%), are central to this process . During brewing, nine phenolic acids are produced, with ferulic acid being the most common . Fine-tuning these brewing parameters ensures better ingredient formulation.
Ingredient Choice and Design
Beer and hops naturally contain prenylated flavonoids like isoxanthohumol and xanthohumol, typically found in concentrations between 0.04 and 3.2 μg/L . Modern brewing methods have improved the absorption of these compounds. For instance, IMPOSSIBREW®'s Social Blend™ technology is designed to enhance bioavailability and deliver measurable benefits for consumers .
"Nutritional therapy, for example through beer, is the best solution to human chronic diseases." - Yawen Zeng
Body Chemistry and Absorption
Individual body chemistry also plays a major role in absorption. The intestinal microbiota is a good example - Eubacterium limosum bacteria can convert isoxanthohumol into 8-prenylnaringenin with an impressive 90% efficiency . However, this conversion rate varies between individuals. Typically, peak absorption happens 30-45 minutes after consumption .
Here are some key factors that affect absorption:
| Factor | Impact on Bioavailability |
|---|---|
| Body Weight | Influences metabolism rate and how compounds are distributed |
| Gender | Affects enzymatic activity and absorption patterns |
| Age | Alters digestive efficiency and metabolism |
| Health Status | Determines overall absorption capability |
| Food Presence | Can either help or hinder ingredient absorption |
Improving Ingredient Absorption
Absorption Methods
Optimizing ingredient absorption is key to maximizing health benefits. Modern brewing techniques have refined how ingredients are integrated. Using natural adjuncts - like fruits, vegetables, and herbs - during brewing boosts the extraction of beneficial compounds. For example, adding adjuncts during the wort boiling stage enhances the extraction of phenolic compounds, while plant additions during fermentation promote the production of bioactive compounds. Specific strategies, such as incorporating dried magnolia berries during wort boiling, significantly increase lignans like schisandrin, gomisin A, and gomisin B .
Here’s a quick breakdown of absorption methods and their effects:
| Method | Benefit | Example Result |
|---|---|---|
| Wort Boiling Addition | Better extraction of phenolic compounds | 37.09% increase in phenolic content with T. herba |
| Fermentation Stage | Boosted bioactive production by yeast | Improved pH and titratable acidity with persimmon fruit |
| Maturation Phase | Higher retention of bioactive compounds | Increased antioxidant levels with Parastrephia lucida |
Testing and Measurement
To evaluate absorption, researchers often use the Caco-2 cell model, which shows that beer polyphenols have an intestinal permeability of 15–25% . Studies focus on two key factors: bioaccessibility (how well compounds are released from the beer matrix) and bioavailability (how much is absorbed, as measured by metabolites in blood or urine). These testing methods highlight practical strategies for improving ingredient absorption.
Case Study: IMPOSSIBREW® and Absorption
IMPOSSIBREW® has applied advanced brewing techniques to refine ingredient absorption. Their proprietary Social Blend™ technology is designed to optimize the uptake of functional ingredients while preserving the beer’s flavor. Their Enhanced Lager and Enhanced Hazy Pale products use specific brewing methods to improve the absorption of nootropic and adaptogenic compounds.
This approach aligns with research showing that the timing of natural adjunct additions during brewing can significantly increase polyphenol content and antioxidant activity compared to standard brewing methods . Additionally, IMPOSSIBREW® tailors its grain selection to improve the absorption of bioactive compounds, ensuring that even their gluten-free beers deliver enhanced nutritional benefits.
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Future Developments
The functional beer industry is on the brink of exciting advancements, with new technologies and evolving regulations set to shape its future.
New Absorption Technology
Nanotechnology is revolutionizing how functional ingredients are delivered in beer. Techniques like nanoencapsulation protect sensitive bioactive compounds, ensuring they remain effective and improving their delivery to the body . For example, researchers at Brno University of Technology have created magneto/catalytic ALG@yeast-Fe3O4 BioBots. These BioBots combine yeast, alginate polymer, and magnetic Fe3O4 nanoparticles. The result? Better fermentation efficiency and easier yeast separation .
| Technology Feature | Benefit | Performance Metric |
|---|---|---|
| Nanoencapsulation | Preserves bioactive ingredients and keeps them stable | Improved ingredient stability |
| BioBots System | Increases fermentation efficiency with biocatalytic propulsion | Supports up to 4 fermentation cycles |
| Magnetic Separation | Simplifies yeast removal for clearer beer without extra steps | Streamlined process, no filtration needed |
As these technologies evolve, the regulatory landscape is also adapting to support these advancements.
Health Claim Regulations
The Alcohol and Tobacco Tax and Trade Bureau (TTB) is introducing new rules requiring more detailed ingredient labeling. This change aligns with consumer demand for transparency: surveys show 91% of people want ingredient lists, 94% support alcohol content disclosure, and 89% want calorie information .
Custom Formula Development
In 2023 alone, the functional beer market saw 258 new product launches aimed at delivering specific health benefits . Brands are experimenting with cutting-edge ingredients like probiotics, adaptogens, and nootropics to cater to wellness-focused consumers. Emerging technologies, such as Social Blend™, are enabling manufacturers to refine formulas based on personalized data.
This push for personalized nutrition is particularly appealing to Gen Z and Millennials, reflecting a broader trend toward tailored health solutions in functional beer. Enhanced ingredient bioavailability remains a key focus as these innovations gain momentum.
Conclusion
Main Points
The bioavailability of functional beers depends on brewing techniques, the choice of ingredients, and individual physiology. The timing of when ingredients are added plays a major role. For example, adding ingredients during the wort boiling stage results in higher bioavailability of phenolic compounds .
The industry has also introduced new methods to improve ingredient absorption. One example is IMPOSSIBREW®'s Social Blend™ technology. This science-based approach, protected by a patent application (GB2415685.3), has shown promising results, with 71% of users reporting improved relaxation effects .
Consumer Options
With these insights, consumers can make smarter choices to maximize ingredient absorption. When choosing functional beers, keep these factors in mind:
| Factor | Impact | What to Look For |
|---|---|---|
| Ingredient Timing | Phenolic content increases with wort boiling | Clear details about the brewing process |
| Compound Source | 70% derived from malt, 30% from hops | Transparent ingredient labels |
| Individual Response | Varies based on body chemistry | Products with third-party testing certifications |
Non-alcoholic options like IMPOSSIBREW® provide benefits without the downsides of alcohol. In fact, 88% of their customers reported cutting back on alcohol consumption after trying their products .
To get the most out of functional beers, it’s essential to consider how your body processes ingredients and opt for products with clear ingredient details and proven absorption techniques.
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What is IMPOSSIBREW®?
IMPOSSIBREW® is a pioneering non-alcoholic beer brand based in the UK that aims to create the world's most complete alcohol alternative using patent-pending technology.
Founded by Mark Wong in 2021 and working with some of the world's best professors, scientists and expert brewers, IMPOSSIBREW® specialises in expertly crafted non-alcoholic beers designed to match full ABV beers in both taste and feeling.
Product Range
IMPOSSIBREW® offers a range of enhanced non-alcoholic beers, including:
- Enhanced Lager (0.5% ABV)
- Enhanced Pale Ale (0.5% ABV)
- Limited Editions (Seasonal)
Key Benefits
The key feature that sets IMPOSSIBREW® apart is its proprietary "Social Blend™" - a combination of active botanical ingredients and nootropics using patent-pending technology* designed to recreate the relaxing effects of alcohol without the negative side effects.
Along with record-breaking quality flavour that comes from a unique process without removing alcohol.
Social Blend™ Ingredients
Developed with leading scientists in top UK universities, Social Blend™ includes:
- L-Theanine
- Ashwaghanda
- Soluble Plant Fibres
- Vitamin B1
- Various Plant Extracts.
These ingredients are chosen for their potential to boost serotonin, promote relaxation, and create a calming effect similar to the "one or two pint feeling" without hangovers.
See more details on our very own research paper, with over 1,000 participants:
- More than 70% said they felt relaxed after consuming IMPOSSIBREW®.
- 88% have reduced alcohol consumption since discovering IMPOSSIBREW®.
- 95% have told a friend about IMPOSSIBREW® after trying.
- 3/4 say that IMPOSSIBREW® is "the most complete alcohol alternative currently available on the market today".
Recognition
IMPOSSIBREW® has received several notable achievements:
- Featured on BBC's Dragons' Den
- Awarded the first and only Gold Medal in the No/Low beer category from the London Beer Competition
- Received multiple industry Gold awards in categories against Full-ABV beers
- Most followed No/Low Alcohol brand on TikTok globally.
Mission and Vision
IMPOSSIBREW® is on a mission to redefine non-alcoholic drinking by creating better-than-alcohol alternatives for those who love beer but want to avoid the health risks associated with alcohol consumption.
The company aims to become the global leading alcohol alternative brand, focusing on helping people transition to a healthier mode of relaxation without the traditional issues and side effects of alcohol.
Production and Ingredients
IMPOSSIBREW® combines traditional brewing methods with their proprietary Social Blend™ along with patent-pending technology*
The beers are made with traditional brewing ingredients such as water, malted barley, wheat, hops, and yeast, in addition to the Social Blend™ components - leveraging their unique cryogenic fermentation process, which means no alcohol is ever removed from the product - ensuring the most authentic quality taste you've come to expect.
Who is it for?
IMPOSSIBREW® caters to consumers who:
- Are busy professionals and parents who would like to unwind with a drink but don't want the hangovers.
- Enjoy the taste and relaxing experience of beer
- Are looking for healthier alternatives to alcohol, with lower calories, carbs and sugar
- Want to avoid hangovers and other negative effects of alcohol consumption
- Are interested in functional beverages with potential mood-enhancing properties
By offering a unique product that aims to replicate both the taste and feeling of alcoholic beer, IMPOSSIBREW® is positioning itself at the forefront of the growing non-alcoholic beverage market.
Get Started Today
Give it a try today with our Welcome Bundle and get 2 Free Beers with your first purchase. Get it delivered straight to your door, risk-free with our 30-day money-back guarantee.
We hope you enjoy them as much as we do and we can't wait for you to try.
*Patent pending in the UK under application number GB2415685.3
How does 'Social Blend™' work?
Social Blend™ is our proprietary alcohol alternative made from a blend of science-backed ingredients using patent-pending technology*.
Designed to replicate the sensory and social relaxing experience of drinking, minus the headaches (and bad decisions).
Developed with Dr Paul Chazot, Bioscience Professor and Chair of Pharmacology at Durham University.
Key Components and Mechanisms
- L-Theanine:
- Ashwagandha Root:
- Vitamin B1 (Thiamine):
- Various nootropic herbs:
Benefits
- Relaxation: The blend promotes a state of relaxation without the sedative effects typically associated with alcohol.
- Mental Calm: By boosting alpha brain waves and serotonin levels, it helps maintain a calm and focused mental state.
- Stress Relief: The combination of L-Theanine, Ashwagandha, and Vitamin B1 helps mitigate stress and anxiety.
- Mood Enhancement: The inclusion these ingredients and other botanicals supports mood regulation and overall positive outlook.
IMPOSSIBREW®'s Social Blend™ is a carefully crafted combination of nootropic and adaptogenic ingredients designed to offer a relaxing and mood-enhancing experience without the drawbacks of alcohol. It leverages the natural properties of its components to promote relaxation, reduce stress, and enhance mood, making it a unique alternative to traditional alcoholic beverages.
(Read our latest research paper here)
*Patent pending in the UK under application number GB2415685.3
Do you ship overseas?
We ship to the UK Mainland for free when you spend over £35
We aim to expand internationally soon - stay tuned!
If you have any queries, feel free to email: hello(@)impossibrew.co.uk
How long will it take to get my orders?
For UK mainland deliveries, normal orders processed here will take 1-3 business days to arrive, with an optional upgrade to Next Day Delivery available (12pm cut-off).
Delivery details will be provided in your confirmation email.
How is 0.5% ABV alcohol-free?
Yes, we know it's confusing. Isn't 0.5% ABV still alcoholic? Officially, 0.5% ABV is classified as Dealcoholised.
- In fact, most things we consume daily have more than 0.5% ABV
- Burger Rolls - 1.2% ABV
- Orange Juice - 0.5% ABV
- Ripe Banana - 0.5% ABV
After more than 2 years of research, we've found that the 0.5% ABV from our natural brewing process significantly increases both flavour and mouthfeel - without spiking your blood alcohol level (BAC).
Is it really gluten-free?
Yes, IMPOSSIBREW® Enhanced Lager is gluten-free. Even though it contains wheat and barley, our beers have been third-party tested to contain less than 10 parts per million (PPM) of gluten, which meets the criteria to be listed as, and labeled gluten-free.
Does it have alcohol tax?
No. While it is true that our beers don't contain alcohol, and thus don't incur UK alcohol duty, we'd like to highlight some factors here that might be helpful in reflecting the value we provide.
- One-to-One Brewing Process: At IMPOSSIBREW, we take pride in our unique brewing techniques. Unlike other non-alcoholic beers, our products are never diluted, watered-down, or have their alcohol content removed - and some even dilute their alcoholic beers up to 5x. This means that our brewing process involves the same level of craftsmanship, time, and resources as a traditional craft beer, resulting in comparable production costs.
- Effective Nootropics: In our commitment to creating the most relaxing non-alcoholic beers, we utilise only the highest quality nootropics as our active ingredients, in safe and effectives dosages. At current alcohol tax rates for a 5% ABV beer, the cost of our nootropics more than double that. Instead of contributing the amounts as tax, why not have it contribute to the product quality itself?
- Small Scale Brewing: Currently, we operate on a smaller scale, which makes us less competitive than large, commercial brewers (often +10,000x our brewing size). As a growing business, we are passionate about our mission to create unique, high-quality non-alcoholic experiences, and we truly appreciate your support. As we continue to grow and expand our production capabilities, we look forward to passing on even more savings to our valued community!
At IMPOSSIBREW, we prioritise offering our customers an enhanced, premium, non-alcoholic beer experience by combining innovative brewing techniques, quality active nootropic ingredients, and award-winning taste. While our pricing may differ from other non-alcoholic competitors, we believe that the value proposition and unique experience our beers provide are well worth it.
At the end of the day, tasting is believing. So give it a try and let us know what you think - risk-free with our IMPOSSIBREW® Guarantee.
Who shouldn't drink IMPOSSIBREW®?
It is not recommended for pregnant or breastfeeding women, those with certain medical conditions like GI disorders or hypertension, or individuals taking specific medications such as antidepressants or blood thinners. If you fall into any of these categories, it's best to consult with your doctor first.
Ashwagandha can lead to overstimulation (i.e. restlessness) if taken alongside thyroid medication.
What is your philosophy?
For thousands of years, we had only one way to unwind together. One way to let our guards down. One way to bridge the gap between who we are and who we are with others.
Not because it was perfect. But because it was all we had.
We decided that wasn't good enough.
We exist because we believe in a world where social connection doesn't demand compromise.
Where being present with others doesn't mean being absent from yourself. Where letting go doesn't mean losing control.This isn't about removing alcohol. This is about something better.
Our Social Blend™ technology isn't an accident. It's the result of questioning everything we thought we knew about social drinking. About working with scientists to understand what we're really seeking in these moments of connection. About daring to imagine something that wasn't possible before.
We believe the greatest innovations don't just solve problems - they change how we live. They make us question why we ever settled for less.
That's what we're building. Not just a drink, but a new way forward. A future where social connection comes without compromise. Where tradition meets innovation. Where science meets ritual.
This is the future of social drinking.
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